Paracetamol overdosage

Question #9184

57 days ago

4,226

Paracetamol overdosage - #9184

Harish

My friend had taken 8 tablets of dolo 650mg with alcohol we seen that and we given mucinac 600 tablets and after 1week again he had taken 15tablets of dolo660with alcohol and after 36hours again he had taken 8tablets of dolo650mg with alcohol any problem will there?

Age: 29

Paracetamol

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Doctors’ responses

Dr. Mayuri Kakoti

I am a dedicated medical professional with extensive clinical experience spanning both emergency care and specialized women's health. At GBH American Hospital, I spent nine months immersed in hands-on patient care and emergency management. This role allowed me to sharpen my clinical assessment skills and develop a keen ability to manage acute medical situations with precision and compassion. My commitment to comprehensive patient care deepened during my 21-month tenure at AIIMS Guwahati. In the Obstetrics and Gynecology department, as well as in trauma and emergency care, I managed a diverse array of critical cases. I actively participated in complex procedures related to women’s health, trauma stabilization, and acute care, ensuring that every patient received immediate and effective treatment. Working in these high-pressure environments has equipped me with a robust foundation in both preventative and emergency medical practices. My approach is firmly rooted in evidence-based medicine, and I continuously strive to enhance my skills through ongoing professional development. I believe that successful healthcare hinges on a blend of technical expertise, compassionate patient interactions, and a relentless commitment to excellence. By integrating my clinical experiences with a patient-centered focus, I aim to deliver the highest standard of care in every aspect of my practice.

57 days ago

Please take him to a doctor immediately. This is not something to wait on or manage at home. Time is critical in acetaminophen poisoning.

Accepted response

3 replies

Harish

Client

57 days ago

Mam we had given mucinac 600tablets to him is that prevent from poisoning?

Dr. Mayuri Kakoti

57 days ago

Giving Mucinac 600 (N-Acetylcysteine, NAC) was a good step, but it may not be enough to fully prevent liver damage, especially with repeated overdoses and alcohol use.

Why?
	1.	Dose & Timing Matter – NAC is most effective when given within 8-10 hours of overdose. After that, its effectiveness decreases, but it can still help.
	2.	Repeated Overdoses – Your friend has taken large doses multiple times, increasing the risk of delayed liver failure even if there are no immediate symptoms.
	3.	Alcohol Increases Risk – Alcohol depletes liver enzymes, making acetaminophen even more toxic.

What to Do Now?
	•	Take him to the hospital immediately – He needs liver function tests (LFTs), INR, and blood tests to check for toxicity.
	•	Doctors may need to give IV NAC – The oral dose you gave may not be enough.
	•	Watch for Symptoms – Nausea, vomiting, abdominal pain, yellowing of skin/eyes (jaundice), confusion, or excessive tiredness require emergency care.

This is serious and potentially life-threatening. Do not wait for symptoms to appear—get medical help now.

Harish

Client

57 days ago

There are no symptoms upto now he was like asusual

Dr. Aman Shaba

Dr. Aman Shaba is a highly qualified Consultant Neuropsychiatrist with extensive clinical experience in diagnosing and managing psychiatric disorders. His expertise spans across general psychiatry, neuropsychiatry, addiction medicine, sexual medicine and psychotherapeutic interventions. Educational Background Dr. Shaba completed his MBBS from M.I.M.E.R Medical College, Pune, where he developed a strong foundation in medical sciences and clinical medicine. His passion for mental health led him to pursue a Doctor of Medicine (MD) in Psychiatry at Jawaharlal Nehru Medical College (JNMC), Wardha. During his postgraduate training, he gained hands-on experience in managing a wide range of psychiatric disorders, neuropsychiatric conditions, and crisis interventions.Dr. Aman Shaba has also completed specialized training in Sexual Medicine from Allo Health, further enhancing his expertise in diagnosing and managing sexual health concerns Professional Experience Dr. Aman Shaba has worked in several esteemed institutions, providing specialized psychiatric care: 1.JNMC, Wardha – As a psychiatry resident, he was actively involved in patient care, research, and academic activities. 2.Deep Chand Bandhu Hospital, Delhi – He played a crucial role in the Children and Adolescent De-addiction Ward, helping young individuals struggling with substance use disorders. His work involved detoxification, behavioral therapy, and relapse prevention strategies tailored to adolescent mental health needs 3.Tele MANAS, Jharkhand (CIP Ranchi) – Currently, he is associated with Tele MANAS, a national tele-mental health service under the Central Institute of Psychiatry (CIP), Ranchi. He provides expert psychiatric consultations via telemedicine, enhancing accessibility to mental healthcare across India.

57 days ago

This is a serious case of paracetamol poisoning, which can be life-threatening. Your friend has repeatedly taken a toxic dose of paracetamol (Dolo 650) with alcohol, which significantly increases the risk of acute liver failure and other complications.

Immediate Actions Required:
Seek emergency medical help immediately – Liver function tests (LFT), PT/INR, and blood ammonia levels need to be checked. N-acetylcysteine (NAC) IV treatment may be necessary to prevent further liver damage.

Monitor for symptoms of liver damage – If there are signs like abdominal pain, vomiting, yellowing of eyes or urine, confusion, or unconsciousness, urgent hospitalization is required.

Alcohol makes paracetamol overdose more toxic, increasing the chances of severe liver injury, so ICU admission may be necessary in critical cases. Do not self medicate the patient, kindly bring this patient to Emergency department asap.

Understanding the Cause of Repeated Overdose:
Since your friend has overdosed multiple times, this could indicate intentional self-harm or an underlying mental health issue like depression, anxiety, or emotional distress. Identifying the root cause is crucial.

A psychiatric evaluation is essential to assess suicidal thoughts and overall mental health.

Emotional and social support is important—family and friends should provide a strong support system.

Future overdose prevention is necessary—stress management and proper psychiatric treatment can help reduce the risk of recurrence.

This is not just a medical emergency but also a serious mental health concern. Immediate medical and psychiatric intervention is necessary.

Dr Aman Shaba 
Consultant Psychiatrist

2 replies

Harish

Client

57 days ago

Is this causes any death situation if we take light here?

Dr. Aman Shaba

57 days ago

Yes... this is serious condition and can be fatal. Do not take this lightly.Take him to emergency department 

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Paracetamol overdosage - #9184

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